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Toxicity of synthetic drugs vs. natural chemicals<\/strong><\/p>\n\n\n\n Natural chemicals<\/strong> have always\nbeen with us since human life began. We might not know them but they are in the\nfoods we eat and the herbs we ingest when we are ill. <\/p>\n\n\n\n Synthetic chemicals<\/strong> are made mostly from petroleum chemicals. We have no long history of intimate contact\nwith them and don\u2019t know whether or not they are edible or poisonous.<\/p>\n\n\n\n We know two chemicals with the same chemical structure are indeed the\nsame chemical, whether they are synthetic or natural. However, the synthetic chemicals are\nmostly made from brand-new ones. Even\nthough some may have been synthesized from natural compounds, their final product\nand the various intermediates as well as byproducts formed during the synthetic\nprocess, are brand new. When we attempt\nto purify the end product, we try to remove as much as possible these brand-new,\npotentially very toxic, intermediates and byproducts. Despite our advanced scientific technologies,\nI am not aware of our being able to remove every single molecule of these\nunwanted compounds we call impurities, from our drugs. Nor do I know of any drug-development\norganizations testing the toxicity of every one of these impurities as they do\nwith drugs. If I am wrong, would someone\nknowledgeable please correct me? <\/p>\n\n\n\n With natural chemicals<\/strong>, we don\u2019t have\nthis problem, because whatever impurities present have already been there with\nthe isolated chemical since antiquity, before and after it is extracted. Take psilocybin, for example, other compounds\n(such as psilocin, baeocystin & norbaeocystin, among others) may already be\npresent, before and after the psilocybin is isolated from the mushroom. <\/p>\n\n\n\n <\/strong>However, in synthetic psilocybin<\/strong>, whatever compounds present with it as\nimpurities, are brand new to this planet. \nThus, its safety is totally unknown. <\/p>\n\n\n\n <\/strong>Incidentally, no chemical, natural or\nsynthetic, is 100.00% pure except theoretically. In practice, the percentage of\nimpurities allowed in pharmacopoeias such as the USP, range from maybe 1% to\n10% or higher. The lower level usually\nis reserved for synthetics and the higher one reserved for naturals. I am not\nsure if those levels have been set because USP scientists knew synthetics are\nunknown hence their safety too, so restrict it to a lower limit; but natural\nchemicals are present along with our foods and herbs since antiquity and hence\nhave at least some safety record. These\nnumbers also make allowance for the precision of the measuring equipment\nused. I know USP tests certain impurities\nin drugs, allowing them to be present in trace amounts. But I don\u2019t know if there are any human\nsafety records for the impurities in synthetic drugs. Does anyone knowledgeable in these matters\nknow?<\/p>\n\n\n\n I don\u2019t know\nabout other drugs, but I believe psilocybin can be obtained by biotechnology,\nor simply stated, \u2018fermentation.\u2019 I\nspent 5 years in graduate school over 50 years ago developing the method which\nproves it is feasible. My work has been published\nin several papers in scientific journals. \nWhoever involved in this business with foresight and compassion for consumers,\ntrying to afford them non-toxic psilocybin, can take up the project. Years of preliminary R&D work can be\neliminated. In addition, baeocystin and\nnorbaeocystin are an added bonus, because sooner or later these 2 compounds\nwill be proven similar or even better than psilocybin in mental healthcare. Good luck to you all! <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n","protected":false},"excerpt":{"rendered":" Toxicity of synthetic drugs vs. natural chemicals Natural chemicals have always been with us since human life began. We might not know them but they are in the foods we eat and the herbs we ingest when we are ill. Synthetic chemicals are made mostly from petroleum chemicals. We have no long history of intimate … <\/p>\n<\/h2>\n\n\n\n