{"id":467,"date":"2020-01-31T18:11:17","date_gmt":"2020-01-31T23:11:17","guid":{"rendered":"http:\/\/ayslcorp.com\/blog\/?p=467"},"modified":"2020-01-31T18:11:17","modified_gmt":"2020-01-31T23:11:17","slug":"natural-vs-synthetic-1-an-issue-for-my-colleagues-to-seriously-consider","status":"publish","type":"post","link":"https:\/\/ayslcorp.com\/blog\/index.php\/2020\/01\/31\/natural-vs-synthetic-1-an-issue-for-my-colleagues-to-seriously-consider\/","title":{"rendered":"Natural vs. synthetic:  1. An issue for my colleagues to seriously consider."},"content":{"rendered":"\n<p><\/p>\n\n\n\n<p> Say we have a new chemical freshly synthesized from a reaction mixture, and it only makes up 75% of the mix.  The rest is mostly unknown intermediates &amp; byproducts from petrochemicals.  We can\u2019t just take it and adjust the drug\u2019s dose to treat patients, because we know there are all these potentially very toxic chemicals in it.  They must be removed by a purification process.   However, after 80 plus years of continuous efforts by scientists trying to develop new or improved drugs, our efforts have led us to the vicious cycle.  The major mistake we have made is the failure to understand the damage these impurities in synthetic drugs can do to patients who take them.  Once we are in our v.c., the monetary incentive to maintain the status quo would be too strong for Big Pharma &amp; Associates to do anything about.  My next post will address the same mistake applied to psilocybin, baeocystin &amp; norbaeocystin and its ramifications. <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23natural&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#natural<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23synthetic&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#synthetic<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23purity&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#purity<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23petrochemicals&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#petrochemicals<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23impurities&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#impurities<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23toxic&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#toxic<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23byproducts&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#byproducts<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23viciouscycle&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#viciouscycle<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23psilocybin&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#psilocybin<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23baeocystin&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#baeocystin<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23norbaeocystin&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#norbaeocystin<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23drugs&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#drugs<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23BigPharma&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#BigPharma<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23statusquo&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#statusquo<\/a> <a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?highlightedUpdateUrns=urn%3Ali%3Aactivity%3A6621454989493624832&amp;keywords=%23monetaryincentive&amp;originTrackingId=%2FXHKZPXXG8k7KHx%2BF%2FWYwg%3D%3D\">hashtag#monetaryincentive<\/a> <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Say we have a new chemical freshly synthesized from a reaction mixture, and it only makes up 75% of the mix. The rest is mostly unknown intermediates &amp; byproducts from petrochemicals. We can\u2019t just take it and adjust the drug\u2019s dose to treat patients, because we know there are all these potentially very toxic chemicals &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/ayslcorp.com\/blog\/index.php\/2020\/01\/31\/natural-vs-synthetic-1-an-issue-for-my-colleagues-to-seriously-consider\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Natural vs. synthetic:  1. An issue for my colleagues to seriously consider.&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-467","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/467","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=467"}],"version-history":[{"count":0,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/467\/revisions"}],"wp:attachment":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=467"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=467"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}