{"id":744,"date":"2026-06-09T09:39:32","date_gmt":"2026-06-09T16:39:32","guid":{"rendered":"https:\/\/ayslcorp.com\/blog\/?p=744"},"modified":"2026-06-09T09:39:32","modified_gmt":"2026-06-09T16:39:32","slug":"this-june-9-2026-post-describes-five-important-issues-affecting-the-toxicity-of-synthetic-drugs-which-standard-scientific-organizations-dont-address","status":"publish","type":"post","link":"https:\/\/ayslcorp.com\/blog\/index.php\/2026\/06\/09\/this-june-9-2026-post-describes-five-important-issues-affecting-the-toxicity-of-synthetic-drugs-which-standard-scientific-organizations-dont-address\/","title":{"rendered":"This June 9, 2026, post describes five important issues affecting the toxicity of synthetic drugs which standard scientific organizations don\u2019t address:\u00a0 \u00a0"},"content":{"rendered":"\n
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  1. Compared to traditional medicines<\/strong> used by us for thousands of years, synthetics<\/strong> have only 150 years of human use history – a tiny fraction.\u00a0 However, being made from toxic petroleum<\/strong>, they are inherently toxic and the scientific tests (in vitro, in vivo, in small animals, etc.) are meant to see how toxic they are before subjecting them to clinical trials in humans;<\/li>\n\n\n\n
  2. Petrochemicals<\/strong> are not the same as plant and animal substances<\/strong> our ancestors tested over countless generations to learn what was edible or medicinal. Many of them people died during that process. Yet some argue that because petroleum is natural, chemicals derived from it are therefore not toxic. I am not aware of any ancestral tradition based on people safely consuming petroleum<\/strong> and passing down that experience.<\/li>\n\n\n\n
  3. Few, if any, of us have also addressed the issue of purity of synthetic drugs<\/strong>.\u00a0 World pharmacopoeias<\/strong> usually list up to a few %. \u00a0But even 1% of an impurity in synthetics can spell serious trouble if that chemical is particularly strong-acting or highly toxic. \u00a0For example, if 1% of LSD is added to psilocybin<\/strong>, a normal dose of the latter containing the LSD<\/strong> would make its psychedelic effects double because LSD is up to 200x stronger acting than psilocybin.\u00a0 Regardless, how many studies of synthetic psilocybin over the past 25 years had unknown strong-acting or toxic impurities<\/strong> therein without the researchers\u2019 knowledge? \u00a0These would \u00a0have obviously distorted our research data.\u00a0 How much of our research literature over the past several decades was based on unsure test objects (drugs)<\/strong>, meaning useless resulting data?\u00a0 \u00a0\u00a0Plenty! Because I have encountered this quite often myself.\u00a0<\/li>\n\n\n\n
  4. Antibiotics<\/strong> (penicillin), steroids<\/strong> (testosterone & cortisone), and opioids<\/strong> (morphine, heroin & fentanyl) are some of the most useful<\/strong> and then abused drugs<\/strong> we have.\u00a0 The fields have turned from a few life savers to increasingly more new drugs being abused along with new diseases that require more new drugs to treat, thus perpetuating the vicious cycle<\/strong> (VC<\/strong>). \u00a0\u00a0And treating<\/strong> drug abuse<\/strong> is itself a booming industry! \u00a0<\/li>\n\n\n\n
  5. No one mentions that our modern drug-therapy process<\/strong> with synthetics is not<\/strong> scientific<\/strong>.\u00a0 Its initial testing on in vitro and in vivo cell systems is scientific, so may be in animals with limited life span (whose results cannot be directly translated to humans).\u00a0 Then, when clinical trials are done on humans for increasingly shorter time before approval, we still have to go through the trial-and-error process<\/strong> in patients \u2013 the same process used by our ancient ancestors thousands of years ago.\u00a0 So, our modern drug development and testing process is not complete (lacking science<\/strong> and\/or human wisdom<\/strong>) without using the trial-and-error step along with its essential time element<\/strong> \u2013 millennia, not just a generation or two.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-744","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/744","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=744"}],"version-history":[{"count":1,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/744\/revisions"}],"predecessor-version":[{"id":745,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/744\/revisions\/745"}],"wp:attachment":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=744"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=744"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=744"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}