{"id":781,"date":"2026-07-02T11:10:54","date_gmt":"2026-07-02T18:10:54","guid":{"rendered":"https:\/\/ayslcorp.com\/blog\/?p=781"},"modified":"2026-07-02T11:11:46","modified_gmt":"2026-07-02T18:11:46","slug":"july-2-2026-post-i-doubt-i-would-have-discovered-the-psilocybin-analogs-if-i-had-not-used-tlc-for-my-analytical-work-just-consider-the-fact-that-it-has-been-almost-60-years","status":"publish","type":"post","link":"https:\/\/ayslcorp.com\/blog\/index.php\/2026\/07\/02\/july-2-2026-post-i-doubt-i-would-have-discovered-the-psilocybin-analogs-if-i-had-not-used-tlc-for-my-analytical-work-just-consider-the-fact-that-it-has-been-almost-60-years\/","title":{"rendered":"July 2, 2026, post.\u00a0 I doubt I would have discovered the psilocybin analogs if I had not used TLC for my analytical work.\u00a0\u00a0\u00a0 Just consider the fact that it has been almost 60 years since I got my PhD from Michigan, no one has succeeded in growing Psilocybe baeocystis or any other psychedelic mushroom and produced mycelia that contained psilocybin and its analog(s).\u00a0"},"content":{"rendered":"\n

I had published all my work in four papers by 1969.  And I am never interested in making money by exploiting or restricting others.  This is unusual, especially after I rejoined the psychedelic movement only about six years ago when the field was filled with \u2018goldrush\u2019 entrepreneurs, especially one group was first a non-probit organization getting free advice and services from well-known experts but then went for-profit and got most of the typical moneyed investors.  They are all sticking to synthetic psychedelics and seem not to be aware of the vicious cycle<\/strong> (VC<\/strong>) of synthetic drug<\/strong> therapy that I have been talking about for years. <\/p>\n\n\n\n

During most of my long independent career I have not dealt with psychedelics.   And I was only employed fulltime for less than six years by two companies.  I came back to magic mushrooms after retirement because I reactivated my membership in LinkedIn<\/strong> to try to promote my book, My Life & Rollercoaster Career<\/strong>, self-published in 2018 (CreateSpace\/Amazon), which is my memoir<\/strong> and my Newsletter<\/strong> (1996-2004) combined.  It did not have anything on psychedelics, except a short description of my PhD research when isolating norbaeocystin<\/strong> and I spilled the concentrated extract ready for crystallization.  When back on LinkedIn, I quickly noticed the chatter online about psilocybin and magic mushrooms.  I promptly forgot my book.  But I found out one key thing that prompted me to eventually form my PBN Naturals Worldwide Consortium<\/strong>.  Incidentally, norbaeocystin is the closest analog to serotonin<\/strong> and psilocybin.  After it is dephosphorylated, it becomes 4-hydroxytryptamine<\/strong>, a nonidentical twin of 5-hydroxytryptamine<\/strong> (=serotonin).  Since serotonin is a hormone and neurotransmitter present throughout our body, its function as a serotonin substitute has never been studied.<\/p>\n\n\n\n

I grew my fungal mycelium in different vessels, flasks of different sizes on shakers and eventually in a home-make 5-gallon Carboy fermenter with aeration.  The mycelia all grew into little pellets up to maybe 0.5 cm in diameter.  I collected the little pellets by screening or filtering them through a sieve or coarse filter, rinsing them with distilled water and freeze-drying them.  Then, I\u2019d do my isolation of their psychedelic compounds.  All the time I was working with growing and extracting the fungal mycelia, I never realized my process would produce a truly clean and natural mycelia containing PBN<\/strong> with NO<\/strong> synthetic contaminants<\/strong> from toxic fossil fuels, or new unknown chemicals from biotech conversions that would require isolation and extraction from synthetic brand-new chemicals with which we have no history of interactions.<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

I had published all my work in four papers by 1969.  And I am never interested in making money by exploiting or restricting others.  This is unusual, especially after I rejoined the psychedelic movement only about six years ago when the field was filled with \u2018goldrush\u2019 entrepreneurs, especially one group was first a non-probit organization … <\/p>\n

Continue reading “July 2, 2026, post.\u00a0 I doubt I would have discovered the psilocybin analogs if I had not used TLC for my analytical work.\u00a0\u00a0\u00a0 Just consider the fact that it has been almost 60 years since I got my PhD from Michigan, no one has succeeded in growing Psilocybe baeocystis or any other psychedelic mushroom and produced mycelia that contained psilocybin and its analog(s).\u00a0“<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-781","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=781"}],"version-history":[{"count":2,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/781\/revisions"}],"predecessor-version":[{"id":783,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/781\/revisions\/783"}],"wp:attachment":[{"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=781"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=781"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ayslcorp.com\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}