Psilocybin(P) Norbaeocystin(N) Baeocystin(B) Aeruginascin(A) Serotonin(S)
2 methyls no methyl 4-OH 1 methyl 3 methyls no methyl 5-OH
Although this post specifically lists the closest analogs simultaneously to psilocybin and serotonin, the vicious cycle (VC) applies to them as well. The PBN Naturals mycelia, especially the B therein when dephosphorylated in the brain becomes an unidentical twin of serotonin. Will it help serotonin perform its brain functions when needed among others in the rest of our body? Thus, norbaeocystin with its phosphate removed becomes 4-hydroxytryptamine that is practically a twin of 5-hydroxytryptamine (also called serotonin).
In my last post of June 2, 2026, I again stressed the vicious cycle (VC) when using synthetic chemicals. Unlike herbal medicines, they are brand new to our planet and all have inherently toxic effects because they have no long-term contact or interactions with humans. The longest for synthetics is 150 years while for natural medicines it is countless years or, say, 150 millennia! Nothing has been done with this twin since it was ‘born’ 60 years ago!
Despite our recent forebears’ invention of scientific tests to try synthetic drugs first on cells and animals, eventually clinical trials in humans, we still must go through the same trial-and-error process our ancient ancestors used in developing our traditional medicines. Am I that wrong with my scientific thinking or is it that our system of healthcare is entrenched by greed? Regardless, our modern drug-therapy process using synthetics which includes trial and error of traditional medicines is obviously NOT scientific; it is faux science. But sensibly combining the two would resolve our current VC problems, especially if our country abandoned its failed capitalistic system to be more like the socio-political system of Canada or Scandinavia whose governments handle their people’s healthcare.
Hence, in the USA, the VC is owned by drug and insurance companies. They have all the incentives to keep it private and ongoing in perpetuity, as it has already been doing for several decades. Which is why we have so many ill people and the world’s highest drug costs. For years we have not been ranked among the world’s 30 or 40 healthiest nations, despite we are the richest and most scientifically advanced, both now debatable.